| Rank | QBs | Team | Year | Game | PCT | Pass Yds | YPA | Pass TD | INT | Rus Yds | Rush TD | Fumble |
| 1 | Patrick Mahomes | Chiefs | 7 | 1 | 53.8 | 226 | 5.8 | 2 | 1 | 45 | 0 | 0 |
| 2 | Jalen Hurts | Eagles | 4 | 1 | 66.7 | 170 | 5.2 | 1 | 0 | 37 | 0 | 1 |
| 3 | Tua Tagovailoa | Dolphins | 4 | 1 | 66.2 | 466 | 10.4 | 3 | 1 | 5 | 0 | 2 |
| 4 | Justin Herbert | LA Chargers | 4 | 1 | 69.7 | 228 | 6.9 | 1 | 0 | 18 | 1 | 0 |
| 5 | Trevor Lawrence | Jaguars | 3 | 1 | 75.0 | 241 | 7.5 | 2 | 1 | 21 | 0 | 1 |
| 6 | Joe Burrow | Bengals | 4 | 1 | 45.2 | 82 | 2.6 | 0 | 0 | -1 | 0 | 0 |
| 7 | Lamar Jackson | Ravens | 6 | 1 | 77.3 | 169 | 7.7 | 0 | 1 | 38 | 0 | 2 |
| 8 | Josh Allen | Bills | 6 | 1 | 70.7 | 236 | 5.8 | 1 | 3 | 36 | 0 | 0 |
| 9 | Brock Purdy | 49ers | 2 | 1 | 65.5 | 220 | 7.6 | 2 | 0 | 20 | 0 | 2 |
| 10 | Jared Goff | Lions | 8 | 1 | 62.9 | 253 | 7.2 | 1 | 0 | -1 | 0 | 0 |
| 11 | Russell Wilson | Broncos | 12 | 1 | 79.4 | 177 | 5.2 | 2 | 0 | 1 | 0 | 0 |
| 12 | Dak Prescott | Cowboys | 8 | 1 | 54.2 | 143 | 6.0 | 0 | 0 | 6 | 0 | 0 |
| 13 | Matthew Stafford | LA Rams | 15 | 1 | 63.2 | 334 | 8.8 | 0 | 0 | 11 | 0 | 0 |
| 14 | Jordan Love | Packers | 4 | 1 | 55.6 | 245 | 9.1 | 3 | 0 | 12 | 0 | 1 |
| 15 | Derek Carr | Saints | 10 | 1 | 69.7 | 305 | 9.2 | 1 | 1 | 4 | 0 | 0 |
| 16 | Mac Jones | Patriots | 3 | 1 | 64.8 | 316 | 5.9 | 3 | 1 | 15 | 0 | 0 |
| 17 | Geno Smith | Seahawks | 11 | 1 | 61.5 | 112 | 4.3 | 1 | 0 | 6 | 0 | 0 |
| 18 | Jimmy Garoppolo | Raiders | 10 | 1 | 76.9 | 200 | 7.7 | 2 | 1 | 11 | 0 | 1 |
| 19 | Deshaun Watson | Browns | 7 | 1 | 55.2 | 154 | 5.3 | 1 | 1 | 45 | 1 | 1 |
| 20 | Kirk Cousins | Vikings | 12 | 1 | 75 | 344 | 7.8 | 2 | 1 | 7 | 0 | 0 |
| 21 | Daniel Jones | Giants | 5 | 1 | 53.6 | 104 | 3.7 | 0 | 2 | 43 | 0 | 2 |
| 22 | Justin Fields | Bears | 3 | 1 | 64.9 | 216 | 5.8 | 1 | 1 | 59 | 0 | 1 |
| 23 | Baker Mayfield | Buccaneers | 6 | 1 | 61.8 | 173 | 5.1 | 2 | 0 | 11 | 0 | 0 |
| 24 | Sam Howell | Commanders | 2 | 1 | 61.3 | 202 | 6.5 | 1 | 1 | 11 | 1 | 1 |
| 25 | Anthony Richardson | Colts | Rookie | 1 | 64.9 | 223 | 6.0 | 1 | 1 | 40 | 1 | 0 |
| 26 | C.J. Stroud | Texans | Rookie | 1 | 63.6 | 242 | 5.5 | 0 | 0 | 20 | 0 | 1 |
| 27 | Bryce Young | Panthers | Rookie | 1 | 52.6 | 146 | 3.8 | 1 | 2 | 17 | 0 | 1 |
| 28 | Kenny Pickett | Steelers | 2 | 1 | 67.4 | 232 | 5.0 | 1 | 2 | 4 | 0 | 0 |
| 29 | Ryan Tannehill | Titans | 12 | 1 | 47.1 | 198 | 5.8 | 0 | 3 | 5 | 0 | 0 |
| 30 | Desmond Ridder | Falcons | 2 | 1 | 83.3 | 115 | 6.4 | 1 | 0 | -1 | 0 | 1 |
| 31 | Joshua Dobbs | Cardinals | 6 | 1 | 70.0 | 132 | 4.4 | 0 | 0 | -3 | 0 | 3 |
| 32 | Zach Wilson | Jets | 3 | 1 | 66.7 | 140 | 6.7 | 1 | 1 | 6 | 0 |