The Carolina Panthers and San Francisco 49ers’ all-time regular season and playoff records in National Football League history. Here we have listed how many head-to-head fights they have, win, lose, tie, and postponed records with points and more you need to know.
What is Panthers vs 49ers record?
Both teams have played each other 23 times so far, where the Panthers win 13 games and the 49ers win 10 games
Carolina Panthers leading the all-time series 13-10-0
| When | Where | Results |
| 10/09/2022 | San Francisco 49ers @ Carolina Panthers | 37-15 (49ers) |
| 10/27/2019 | Carolina Panthers @ San Francisco 49ers | 13-51 (49ers) |
| 09/10/2017 | Carolina Panthers @ San Francisco 49ers | 23-3 (Panthers) |
| 09/18/2016 | San Francisco 49ers @ Carolina Panthers | 27-46 (Panthers) |
| 01/12/2014 | San Francisco 49ers @ Carolina Panthers | 23-10 (49ers) |
| 11/10/2013 | Carolina Panthers @ San Francisco 49ers | 10-9 (Panthers) |
| 10/24/2010 | San Francisco 49ers @ Carolina Panthers | 20-23 (Panthers) |
| 12/02/2007 | San Francisco 49ers @ Carolina Panthers | 14-31 (Panthers) |
| 11/14/2004 | Carolina Panthers @ San Francisco 49ers | 37-27 (Panthers) |
| 11/18/2001 | San Francisco 49ers @ Carolina Panthers | 25-22 (49ers) |
| 10/07/2001 | Carolina Panthers @ San Francisco 49ers | 14-24 (49ers) |
| 10/22/2000 | San Francisco 49ers @ Carolina Panthers | 16-34 (Panthers) |
| 09/10/2000 | Carolina Panthers @ San Francisco 49ers | 38-22 (Panthers) |
| 12/18/1999 | San Francisco 49ers @ Carolina Panthers | 24-41 (Panthers) |
| 10/17/1999 | Carolina Panthers @ San Francisco 49ers | 31-29 (Panthers) |
| 12/06/1998 | San Francisco 49ers @ Carolina Panthers | 31-28 (49ers) |
| 11/08/1998 | Carolina Panthers @ San Francisco 49ers | 23-25 (49ers) |
| 11/16/1997 | Carolina Panthers @ San Francisco 49ers | 19-27 (49ers) |
| 09/29/1997 | San Francisco 49ers @ Carolina Panthers | 34-21 (49ers) |
| 12/08/1996 | Carolina Panthers @ San Francisco 49ers | 30-24 (Panthers) |
| 09/22/1996 | San Francisco 49ers @ Carolina Panthers | 7-23 (Panthers) |
| 12/10/1995 | San Francisco 49ers @ Carolina Panthers | 31-10 (49ers) |
| 11/05/1995 | Carolina Panthers @ San Francisco 49ers | 13-7 (Panthers) |