The 2022 NFL Week 15 games are scheduled, to begin with, San Francisco will visit Seattle on Thursday, December 15, and ends with a game between the LA Rams vs Green Bay Monday, December 19, 2022.
Thursday, December 15
| Matchup | Time (ET) | TV |
| San Francisco @ Seattle | 8:15 PM | Prime Video |
Saturday, December 17
| Matchup | Time (ET) | TV |
| Miami @ Buffalo | TBA | |
| Baltimore @ Cleveland | TBA | |
| Indianapolis @ Minnesota | TBA | |
| Atlanta @ New Orleans | TBA | |
| NY Giants @ Washington | TBA |
Sunday, December 18
| Matchup | Time (ET) | TV |
| Pittsburgh @ Carolina | 1:00 PM | CBS |
| Philadelphia @ Chicago | 1:00 PM | FOX |
| Kansas City @ Houston | 1:00 PM | CBS |
| Dallas @ Jacksonville | 1:00 PM | FOX |
| Detroit @ NY Jets | 1:00 PM | FOX |
| Arizona @ Denver | 4:05 PM | FOX |
| Tennessee @ LA Chargers | 4:25 PM | CBS |
| Cincinnati @ Tampa Bay | 4:25 PM | CBS |
| New England @ Las Vegas | 8:20 PM | NBC |
Monday, December 19
| Matchup | Time (ET) | TV |
| LA Rams @ Green Bay | 8:15 PM | ESPN |