The 2022 NFL Week 12 games are scheduled, to begin with, Buffalo will visit Detroit on Thursday, November 24, and ends with a game between the Pittsburgh vs Indianapolis Monday, November 28, 2022.
Thursday, November 24
| Matchup | Time (ET) | TV |
| Buffalo @ Detroit | 12:30 PM | CBS |
| NY Giants @ Dallas | 4:30 PM | FOX |
| New England @ Minnesota | 8:20 PM | NBC |
Sunday, November 27
| Matchup | Time (ET) | TV |
| Denver @ Carolina | 1:00 PM | FOX |
| Tampa Bay @ Cleveland | 1:00 PM | FOX |
| Baltimore @ Jacksonville | 1:00 PM | CBS |
| Houston @ Miami | 1:00 PM | CBS |
| Chicago @ NY Jets | 1:00 PM | FOX |
| Cincinnati @ Tennessee | 1:00 PM | CBS |
| Atlanta @ Washington | 1:00 PM | FOX |
| LA Chargers @ Arizona | 4:05 PM | CBS |
| Las Vegas @ Seattle | 4:05 PM | CBS |
| LA Rams @ Kansas City | 4:25 PM | FOX |
| New Orleans @ San Francisco | 4:25 PM | FOX |
| Green Bay @ Philadelphia | 8:20 PM | NBC |
Monday, November 28
| Matchup | Time (ET) | TV |
| Pittsburgh @ Indianapolis | 8:15 PM | ESPN |