2025 NFL WEEK 4 GAME PICKS – FULL WEEK PREDICTIONS
Check out the 2025 NFL Week 4 matchups with locations and predicted scores. See where each team plays and get ready for an exciting week of football action!
| Matchup | Location | Predicted Score |
| Thursday Night | ||
| Seahawks @ Cardinals | State Farm Stadium | SEA 24 – ARI 21 |
| Sunday Night | ||
| Vikings @ Steelers | Acrisure Stadium | PIT 28 – MIN 17 |
| Saints @ Bills | Highmark Stadium | BUF 31 – NO 20 |
| Titans @ Texans | NRG Stadium | HOU 24 – TEN 18 |
| Browns @ Lions | Ford Field | DET 30 – CLE 21 |
| Commanders @ Falcons | Mercedes-Benz Stadium | ATL 24 – WAS 17 |
| Eagles @ Buccaneers | Raymond James Stadium | PHI 30 – TB 18 |
| Panthers @ Patriots | Gillette Stadium | NE 30 – CAR 20 |
| Chargers @ Giants | MetLife Stadium | LAC 32 – NYG 20 |
| Jaguars @ 49ers | Levi’s Stadium | SF 24 – JAX 17 |
| Colts @ Rams | SoFi Stadium | LAR 27 – IND 20 |
| Bears @ Raiders | Allegiant Stadium | CHI 23 – LV 20 |
| Ravens @ Chiefs | Arrowhead Stadium | KC 34 – BAL 31 |
| Packers @ Cowboys | AT&T Stadium | DAL 27 – GB 24 |
| Monday Night | ||
| Jets @ Dolphins | Hard Rock Stadium | NYJ 23 – MIA 20 |
| Bengals @ Broncos | Empower Field | CIN 26 – DEN 22 |