| Opponent | Date | Time (ET) | TV | Venues |
| vs Illinois State Redbirds | Sep. 3 | 7:00 PM | FS1 | Camp Randall Stadium |
| vs Washington State Cougars | Sep. 10 | 3:30 PM | FOX | Camp Randall Stadium |
| vs New Mexico State Aggies | Sep. 17 | 3:30 PM | BTN | Camp Randall Stadium |
| @ Ohio State Buckeyes | Sep. 24 | TBA | ABC | Ohio Stadium |
| vs Illinois Fighting Illini | Oct. 1 | TBA | TBA | Camp Randall Stadium |
| @ Northwestern Wildcats | Oct. 8 | 3:30 or 4 PM | TBA | Ryan Field |
| @ Michigan State Spartans | Oct. 15 | 3:30 PM | TBA | Spartan Stadium |
| vs Purdue Boilermakers (HC) | Oct. 22 | 3:30 PM | TBA | Camp Randall Stadium |
| vs Maryland Terrapins | Nov. 5 | TBA | TBA | Camp Randall Stadium |
| @ Iowa Hawkeyes | Nov. 12 | TBA | TBA | Kinnick Stadium |
| @ Nebraska Cornhuskers | Nov. 19 | TBA | TBA | Memorial Stadium |
| vs Minnesota Golden Gophers | Nov. 26 | TBA | TBA | Camp Randall Stadium |
| vs Big Ten Championship | Dec. 3 | 8:00 PM | FOX | Lucas Oil Stadium |