| Opponent | Date | Time (ET) | TV | Venues |
| @ Old Dominion Monarchs | Sep. 2 | 7:00 PM | ESPNU | S.B. Ballard Stadium |
| vs Boston College Eagles | Sep. 10 | 8:00 PM | ACCN | Lane Stadium |
| vs Wofford Terriers | Sep. 17 | 11:00 PM | ACCN | Lane Stadium |
| vs West Virginia Mountaineers | Sep. 22 | 7:30 PM | ESPN | Lane Stadium |
| @ North Carolina Tar Heels | Oct. 1 | TBA | TBA | Kenan Memorial Stadium |
| @ Pitt Panthers | Oct. 8 | TBA | TBA | Heinz Field |
| vs Miami (FL) Hurricanes (HC) | Oct. 15 | TBA | TBA | Lane Stadium |
| @ NC State Wolfpack | Oct. 27 | 7:30 PM | ESPN | Carter-Finley Stadium |
| vs Georgia Tech Yellow Jackets | Nov. 5 | TBA | TBA | Lane Stadium |
| @ Duke Blue Devils | Nov. 12 | TBA | TBA | Wallace Wade Stadium |
| @ Liberty Flames | Nov. 19 | TBA | TBA | Williams Stadium |
| vs Virginia Cavaliers | Nov. 26 | TBA | TBA | Lane Stadium |
| vs ACC Championship | Dec. 3 | TBA | ABC | Bank of America Stadium |