| Opponent | Date | Time (ET) | TV | Venues |
| vs Alabama A&M Bulldogs | Sep. 1 | 8:00 PM | CBSSN | Protective Stadium |
| @ Liberty Flames | Sep. 10 | 6:00 PM | ESPN+ | Williams Stadium |
| vs Georgia Southern Eagles | Sep. 17 | 3:30 PM | Stadium | Protective Stadium |
| @ Rice Owls | Oct. 1 | 7:30 PM | ESPN network | Rice Stadium |
| vs Middle Tennessee Blue Raiders | Oct. 8 | 3:30 PM | Stadium | Protective Stadium |
| vs Charlotte 49ers | Oct. 15 | 3:30 PM | Stadium | Protective Stadium |
| @ WKU Hilltoppers | Oct. 21 | 8:00 PM | CBSSN | Houchens-Smith Stadium |
| @ Florida Atlantic Owls | Oct. 29 | 7:00 PM | CBSSN | FAU Stadium |
| vs UTSA Roadrunners | Nov. 5 | 3:30 PM | Stadium | Protective Stadium |
| vs North Texas Mean Green | Nov. 12 | 3:30 PM | Stadium | Protective Stadium |
| @ LSU Tigers | Nov. 19 | TBA | TBA | Tiger Stadium |
| @ Louisiana Tech Bulldogs | Nov. 26 | 3:30 PM | CBSSN | Joe Aillet Stadium |
| vs C-USA Championship | Dec. 2 | 8:00 PM | CBSSN | TBD |