| Opponent | Date | Time (ET) | TV | Venues |
| @ Ole Miss Rebels | Sep. 3 | 4:00 PM | SECN | Vaught-Hemingway Stadium |
| vs Alabama A&M Bulldogs | Sep. 10 | 7:00 PM | ESPN3 | Veterans Memorial Stadium |
| @ Appalachian State Mountaineers | Sep. 17 | 3:30 PM | ESPN+ | Kidd Brewer Stadium |
| vs Marshall Thundering Herd | Sep. 24 | 7:00 PM | TBA | Veterans Memorial Stadium |
| @ WKU Hilltoppers | Oct. 1 | 7:00 PM | ESPN network | Houchens-Smith Stadium |
| vs Southern Miss Golden Eagles | Oct. 8 | 7:00 PM | TBA | Veterans Memorial Stadium |
| vs Texas State Bobcats (HC) | Oct. 15 | 3:30 PM | TBA | Veterans Memorial Stadium |
| @ South Alabama Jaguars | Oct. 20 | 7:30 PM | ESPNU | Hancock Whitney Stadium |
| @ Louisiana Ragin’ Cajuns | Nov. 5 | TBA | TBA | Cajun Field |
| vs Army Black Knights | Nov. 12 | 3:30 PM | TBA | Veterans Memorial Stadium |
| vs ULM Warhawks | Nov. 19 | 3:30 PM | TBA | Veterans Memorial Stadium |
| @ Arkansas State Red Wolves | Nov. 26 | TBA | TBA | Centennial Bank Stadium |
| vs Sun Belt Championship | Dec. 3 | 3:30 PM | ESPN | TBD |