| Opponent | Date | Time (ET) | TV | Venues |
| vs Nicholls Colonels | Sep. 3 | 5:00 PM | ESPN3 | Hancock Whitney Stadium |
| @ Central Michigan Chippewas | Sep. 10 | 1:00 PM | ESPN+ | Kelly/Shorts Stadium |
| @ UCLA Bruins | Sep. 17 | 2:00 PM | P12N | Rose Bowl Stadium |
| vs Louisiana Tech Bulldogs | Sep. 24 | TBA | TBA | Hancock Whitney Stadium |
| @ Louisiana Ragin’ Cajuns | Oct. 1 | TBA | TBA | Cajun Field |
| vs ULM Warhawks (HC) | Oct. 15 | TBA | TBA | Hancock Whitney Stadium |
| vs Troy Trojans | Oct. 20 | 7:30 PM | ESPNU | Hancock Whitney Stadium |
| @ Arkansas State Red Wolves | Oct. 29 | TBA | TBA | Centennial Bank Stadium |
| @ Georgia Southern Eagles | Nov. 5 | 4:00 PM | TV TBA | Paulson Stadium |
| vs Texas State Bobcats | Nov. 12 | TBA | TBA | Hancock Whitney Stadium |
| @ Southern Miss Golden Eagles | Nov. 19 | TBA | TBA | M. M. Roberts Stadium |
| vs Old Dominion Monarchs | Nov. 26 | TBA | TBA | Hancock Whitney Stadium |
| vs Sun Belt Championship | Dec. 3 | 3:30 PM | ESPN | TBD |