| Opponent | Date | Time (ET) | TV | Venues |
| @ Purdue Boilermakers | Sep. 1 | 8:00 PM | FOX | Ross-Ade Stadium |
| vs Ohio Bobcats | Sep. 10 | 12:00 PM | ABC | Beaver Stadium |
| @ Auburn Tigers | Sep. 17 | 3:30 PM | CBS | Jordan-Hare Stadium |
| vs Central Michigan Chippewas | Sep. 24 | TBA | BTN | Beaver Stadium |
| vs Northwestern Wildcats | Oct. 1 | TBA | ESPN network | Beaver Stadium |
| @ Michigan Wolverines | Oct. 15 | TBA | TBA | Michigan Stadium |
| vs Minnesota Golden Gophers (HC) | Oct. 22 | 7:30 PM | TBA | Beaver Stadium |
| vs Ohio State Buckeyes | Oct. 29 | TBA | TBA | Beaver Stadium |
| @ Indiana Hoosiers | Nov. 5 | TBA | TBA | Memorial Stadium |
| vs Maryland Terrapins | Nov. 12 | TBA | TBA | Beaver Stadium |
| @ Rutgers Scarlet Knights | Nov. 19 | TBA | TBA | SHI Stadium |
| vs Michigan State Spartans | Nov. 26 | TBA | TBA | Beaver Stadium |
| vs Big Ten Championship | Dec. 3 | 8:00 PM | FOX | Lucas Oil Stadium |