| Opponent | Date | Time (ET) | TV | Venues |
| @ East Carolina Pirates | Sep. 3 | 12:00 PM | ESPN | Dowdy-Ficklen Stadium |
| vs Charleston Sou. Buccaneers | Sep. 10 | 12:30 PM | RSN/ESPN3 | Carter-Finley Stadium |
| vs Texas Tech Red Raiders | Sep. 17 | 7:00 PM | ESPN2 | Carter-Finley Stadium |
| vs UConn Huskies | Sep. 24 | TBA | TBA | Carter-Finley Stadium |
| @ Clemson Tigers | Oct. 1 | TBA | TBA | Memorial Stadium |
| vs Florida State Seminoles | Oct. 8 | TBA | TBA | Carter-Finley Stadium |
| @ Syracuse Orange | Oct. 15 | TBA | TBA | JMA Wireless Dome |
| vs Virginia Tech Hokies | Oct. 27 | 7:30 PM | ESPN | Carter-Finley Stadium |
| vs Wake Forest Demon Deacons (HC) | Nov. 5 | TBA | TBA | Carter-Finley Stadium |
| vs Boston College Eagles | Nov. 12 | TBA | TBA | Carter-Finley Stadium |
| @ Louisville Cardinals | Nov. 19 | TBA | TBA | Cardinal Stadium |
| @ North Carolina Tar Heels | Nov. 25 | 12/1/3:30 PM | ESPN | Kenan Memorial Stadium |
| vs ACC Championship | Dec. 3 | TBA | ABC | Bank of America Stadium |