| Opponent | Date | Time (ET) | TV | Venues |
| vs Buffalo Bulls | Sep. 3 | 12:00 PM | BTN | Maryland Stadium |
| @ Charlotte 49ers | Sep. 10 | 3:30 PM | Stadium | Jerry Richardson Stadium |
| vs SMU Mustangs | Sep. 17 | 7:30 PM | FS1 | Maryland Stadium |
| @ Michigan Wolverines | Sep. 24 | 12:00 PM | FOX or FS1 | Michigan Stadium |
| vs Michigan State Spartans | Oct. 1 | TBA | TBA | Maryland Stadium |
| vs Purdue Boilermakers | Oct. 8 | TBA | TBA | Maryland Stadium |
| @ Indiana Hoosiers | Oct. 15 | TBA | TBA | Memorial Stadium |
| vs Northwestern Wildcats (HC) | Oct. 22 | 3:30 PM | ETTV TBA | Maryland Stadium |
| @ Wisconsin Badgers | Nov. 5 | TBA | TBA | Camp Randall Stadium |
| @ Penn State Nittany Lions | Nov. 12 | TBA | TBA | Beaver Stadium |
| vs Ohio State Buckeyes | Nov. 19 | TBA | TBA | Maryland Stadium |
| vs Rutgers Scarlet Knights | Nov. 26 | TBA | TBA | Maryland Stadium |
| vs Big Ten Championship | Dec. 3 | 8:00 PM | FOX | Lucas Oil Stadium |