| Opponent | Date | Time (ET) | TV | Venues |
| @ Syracuse Orange | Sep. 3 | 8:00 PM | ACCN | JMA Wireless Dome |
| @ UCF Knights | Sep. 9 | 7:30 PM | ESPN2 | Bounce House |
| vs Florida State Seminoles | Sep. 16 | 7:00 PM | ESPN | Cardinal Stadium |
| vs USF Bulls | Sep. 24 | TBA | TBA | Cardinal Stadium |
| @ Boston College Eagles | Oct. 1 | TBA | TBA | Alumni Stadium |
| @ Virginia Cavaliers | Oct. 8 | TBA | TBA | Scott Stadium |
| vs Pitt Panthers | Oct. 22 | TBA | TBA | Cardinal Stadium |
| vs Wake Forest Demon Deacons | Oct. 29 | TBA | TBA | Cardinal Stadium |
| vs James Madison Dukes | Nov. 5 | TBA | TBA | Cardinal Stadium |
| @ Clemson Tigers | Nov. 12 | TBA | TBA | Memorial Stadium |
| vs NC State Wolfpack | Nov. 19 | TBA | TBA | Cardinal Stadium |
| @ Kentucky Wildcats | Nov. 26 | TBA | TBA | Kroger Field |
| vs ACC Championship | Dec. 3 | TBA | ABC | Bank of America Stadium |