Los Angeles Chargers preseason schedule
| Opponent | Date | Time (ET) | TV |
| vs Los Angeles Rams | Aug. 13 | 10:00 PM | NFLN |
| vs Dallas Cowboys | Aug. 20 | 10:00 PM | NFLN |
| @ New Orleans Saints | Aug. 27 | 8:00 PM | Prime Video |
Los Angeles Chargers regular season schedule
| Opponent | Date | Time | TV |
| vs Las Vegas | Sun, 11 Sep | 4:25 PM | CBS |
| @ Kansas City | Thu, 15 Sep | 8:15 PM | Prime Video |
| vs Jacksonville | Sun, 25 Sep | 4:05 PM | CBS |
| @ Houston | Sun, 2 Oct | 1:00 PM | CBS |
| @ Cleveland | Sun, 9 Oct | 1:00 PM | CBS |
| vs Denver | Mon, 17 Oct | 8:15 PM | ESPN |
| vs Seattle | Sun, 23 Oct | 4:25 PM | FOX |
| @ Atlanta | Sun, 6 Nov | 1:00 PM | FOX |
| @ San Francisco | Sun, 13 Nov | 8:20 PM | NBC |
| vs Kansas City | Sun, 20 Nov | 4:25 PM | CBS |
| @ Arizona | Sun, 27 Nov | 4:05 PM | CBS |
| @ Las Vegas | Sun, 4 Dec | 4:25 PM | CBS |
| vs Miami | Sun, 11 Dec | 4:05 PM | CBS |
| vs Tennessee | Sun, 18 Dec | 4:25 PM | CBS |
| @ Indianapolis | Mon, 26 Dec | 8:15 PM | ESPN |
| vs Los Angeles | Sat, 1 Jan | 8:20 PM | NBC |
| @ Denver | Sat, 8 Jan | TBD | TBD |