| Opponent | Date | Time (ET) | TV | Venues |
| vs Miami (Ohio) RedHawks | Sep. 3 | 7:00 PM | SECN+/ESPN+ | Kroger Field |
| @ Florida Gators | Sep. 10 | 7:00 PM | ESPN | Ben Hill Griffin Stadium |
| vs Youngstown State Penguins | Sep. 17 | 12:00 PM | SECN | Kroger Field |
| vs NIU Huskies | Sep. 24 | TBA | TBA | Kroger Field |
| @ Ole Miss Rebels | Oct. 1 | TBA | TBA | Vaught-Hemingway Stadium |
| vs South Carolina Gamecocks | Oct. 8 | TBA | TBA | Kroger Field |
| vs Mississippi State Bulldogs (HC) | Oct. 15 | TBA | TBA | Kroger Field |
| @ Tennessee Volunteers | Oct. 29 | TBA | TBA | Neyland Stadium |
| @ Missouri Tigers | Nov. 5 | TBA | TBA | Faurot Field |
| vs Vanderbilt Commodores | Nov. 12 | TBA | TBA | Kroger Field |
| vs Georgia Bulldogs | Nov. 19 | TBA | TBA | Kroger Field |
| vs Louisville Cardinals | Nov. 26 | TBA | TBA | Kroger Field |
| vs SEC Championship | Dec. 3 | 4:00 PM | CBS | Mercedes-Benz Stadium |