| Opponent | Date | Time | TV | Venues |
| @ Wisconsin Badgers | Sep. 3 | 7:00 PM | FS1 | Camp Randall Stadium |
| vs Valparaiso Beacons | Sep. 10 | 7:30 PM | MSN | Hancock Stadium |
| vs Eastern Illinois Panthers | Sep. 17 | 7:30 PM | MSN | Hancock Stadium |
| vs Southern Illinois Salukis | Oct. 1 | 7:30 PM | MSN | Hancock Stadium |
| @ Northern Iowa Panthers | Oct. 8 | TBA | MSN | UNI-Dome |
| vs South Dakota Coyotes | Oct. 15 | 3:00 PM | ESPN3/+ | Hancock Stadium |
| @ Indiana State Sycamores | Oct. 22 | 1:00 PM | TBA | Memorial Stadium |
| @ North Dakota State Bison | Oct. 29 | 3:30 PM | ABC ND/ESPN+ | Fargodome |
| vs Youngstown State Penguins | Nov. 5 | 3:00 PM | MSN | Hancock Stadium |
| @ South Dakota State Jackrabbits | Nov. 12 | 3:00 PM | TBA | Dana J. Dykhouse Stadium |
| vs Western Illinois Leathernecks | Nov. 19 | 1:00 PM | MSN | Hancock Stadium |