| Opponent | Date | Time (ET) | TV | Venues |
| @ Georgia Tech Yellow Jackets | Sep. 5 | 8:00 PM | ESPN | Mercedes-Benz Stadium |
| vs Furman Paladins | Sep. 10 | 3:30 PM | ACCN | Memorial Stadium |
| vs Louisiana Tech Bulldogs | Sep. 17 | 8:00 PM | ACCN | Memorial Stadium |
| @ Wake Forest Demon Deacons | Sep. 24 | TBA | TBA | Truist Field |
| vs NC State Wolfpack | Oct. 1 | TBA | TBA | Memorial Stadium |
| @ Boston College Eagles | Oct. 8 | TBA | TBA | Alumni Stadium |
| @ Florida State Seminoles | Oct. 15 | TBA | TBA | Doak Campbell Stadium |
| vs Syracuse Orange (HC) | Oct. 22 | TBA | TBA | Memorial Stadium |
| @ Notre Dame Fighting Irish | Nov. 5 | 7:30 PM | NBC | Notre Dame Stadium |
| vs Louisville Cardinals | Nov. 12 | TBA | TBA | Memorial Stadium |
| vs Miami (FL) Hurricanes | Nov. 19 | TBA | TBA | Memorial Stadium |
| vs South Carolina Gamecocks | Nov. 26 | TBA | TBA | Memorial Stadium |
| vs ACC Championship | Dec. 3 | TBA | TBA | Bank of America Stadium |