| Opponent | Date | Time (ET) | TV | Venues |
| @ Arkansas Razorbacks | Sep. 3 | 3:30 PM | ESPN | D.W.R. Razorback Stadium |
| vs Kennesaw State Owls | Sep. 10 | 3:30 PM | ESPN+ | Nippert Stadium |
| vs Miami (Ohio) RedHawks | Sep. 17 | 12:00 PM | ESPNU | Paul Brown Stadium |
| vs Indiana Hoosiers | Sep. 24 | TBA | TBA | Nippert Stadium |
| @ Tulsa Golden Hurricane | Oct. 1 | TBA | TBA | H.A. Chapman Stadium |
| vs USF Bulls (HC) | Oct. 8 | TBA | TBA | Nippert Stadium |
| @ SMU Mustangs | Oct. 22 | TBA | TBA | Gerald J. Ford Stadium |
| @ UCF Knights | Oct. 29 | TBA | TBA | Bounce House |
| vs Navy Midshipmen | Nov. 5 | TBA | TBA | Nippert Stadium |
| vs East Carolina Pirates | Nov. 11 | 7:30 PM | ESPN2 | Nippert Stadium |
| @ Temple Owls | Nov. 19 | TBA | TBA | Lincoln Financial Field |
| vs Tulane Green Wave | Nov. 26 | TBA | TBA | Nippert Stadium |
| vs American Championship | Dec. 3 | 4:00 PM | ABC | Site, City TBD |